| South Country Line Creek | rises in S Caswell County and flows NW into Country Line Creek. |
| South Cox Creek | rises in N Yancey County and flows SE into Jacks Creek. |
| South Creek | rises in SE Beaufort County and flows N and E into Pamlico River. Appears as Chickorack River on the Comberford map, 1657, and as South Dividing Creek on the Collet map, 1770. |
| South Creek | rises in E Chatham County and flows E and S into Wake County, where it enters Big White Oak Creek near the Chatham County line. |
| South Creek | rises in NE Rutherford County and flows NE into First Broad River. |
| South Creek | town in SE Beaufort County on a peninsula formed by the mouths of Bond and Muddy Creeks as they enter Pamlico River. Settled prior to 1794, when it was known as Stanton-Harrold for two men who operated a sawmill there. Apparently known as Harold in the early nineteenth century and as Oregon (for the first steamboat to come up the Pamlico River—see Oregon Inlet) about the middle of the century. Post office, 1851-1954, operated as South Creek. Inc. 1883 as Stanton. Inc. 1925 as South Creek, but no longer active in municipal affairs. |
| South Crowders Creek | rises in S Gaston County and flows SE into Crowders Creek. |
| South Deep Creek | rises in W Yadkin County and flows SE and E to join North Deep Creek in forming Deep Creek. |
| South Dividing Creek | See South Creek. |
| South Double Creek | rises in W Stokes County and flows NE into Dan River. |